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Chronic Kidney Disease is a progressive, long-term condition that affects the overall functioning of kidneys, the vital organs responsible for removing waste and excessive fluids from the blood. It is a gradual process that develops over time and often has only a few obvious kidney disease symptoms at the beginning of its course. But when CKD is ignored or neglected, it can lead to severe complications and possibly kidney failure.
The most common reasons for CKD are:
Diabetes.
Hypertension of the blood (hypertension).
Glomerulonephritis (inflammation of the kidney's filtering unit).
Other causes like smoking, obesity, or family history, and some medications may cause the development of CKD.


This chronic kidney disease can be classified into five stages based on an estimated Glomerular Filtration Ratio (eGFR), which measures the kidney's function. In the beginning stage (1 or 2), kidneys are not severely impaired, but the signs may not be evident. When the condition progresses into stage 3 or 4, symptoms such as fatigue, swelling, changes in the pattern of urination, and anemia can be seen. Stage 5 CKD, also known as kidney disease that is end stage, can be characterized by a severe reduction in eGFR, and kidneys are unable to maintain normal body functions.